cuticleDB is a relational database containing all structural proteins of Arthropod cuticle identified to date. Many come from direct sequencing of proteins isolated from cuticle and from sequences from cDNAs that share common features with these authentic cuticular proteins.It also includes proteins from the five sequenced genomes where manual annotation has been applied to cuticular proteins: Anopheles gambiae, Apis mellifera, Bombyx mori, Drosophila melanogaster, and [Nasonia vitripennis]. Some sequences were confirmed as authentic cuticular proteins because protein sequencing revealed that they were present in cuticle; others were identified by sequence homology and other criteria. Entries provides information about whether sequences are putative or authentic cuticular proteins.

cuticleDB hosts 774 proteins Insecta: 699 entries Crustacea: 60 entries Chelicerata: 15 entries last update: 20 Oct 2009

Christiana K. Magkrioti1, Ioannis C. Spyropoulos1, Vassiliki A. Iconomidou1, Judith H. Willis2 and Stavros J. Hamodrakas1

1Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Athens 157 01 , Greece

2Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA

ACKNOWLEDGEMENTS:This work was supported in part by grant AI055624 from the U.S. National Institutes of Health and the University of Athens.

New:

Distinguish any sequence between RR1 & RR2.

Linking to cuticleDB:
Example for protein AgamCPR1 (cuticleDB ID:639)	http://bioinformatics.biol.uoa.gr/cuticleDB/protview.jsp?id=639

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contact biodbbiol.uoa.gr for comments, corrections and data (sequence) submission.

	University of Athens Faculty of Biology Dept. of Cell Biology and Biophysics	Biophysics & Bioinformatics Laboratory