gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF1462 ::
FAMILY Ion channels
SUBFAMILY Voltage dependent calcium channels
TYPE Voltage dependent N type calcium channel

Cross References:
UniProt O55017 | Q60609 EMBL AF042317 | U04999
InterPro IPR002048 | IPR005821 | IPR005447 | IPR002077
GENEID 12287
PRINTS PR00167 | PR01631 PFAM PF00520

Details:
NAME Voltage dependent N type calcium channel-Mus musculus-2
DESCRIPTION Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage-gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type,alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Cacna1b | Cach5 | Cacnl1a5 | Cchn1a
SEQUENCE
MVRFGDELGGRYGGTGGGERARGGGAGGAGGPGQGGLPPGQRVLYKQSIAQRARTMALYN
PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
GLEFYMGKFHKACFP
FRAGMENT NO
FUNCTION Voltage-sensitive calcium channels (VSCC) mediate thes entry of calcium ions into excitable cells and are also involveds in a variety of calcium-dependent processes, including muscles contraction, hormone or neurotransmitter release, gene expression,s ce
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 11031246
1GPR0021Galpha-o1-Mus musculus
Family:Gbeta REFERENCES:15251227 | 11031246
2GPR0148Gbeta-1-Mus musculus
3GPR0156Gbeta-2-Mus musculus
4GPR0161Gbeta-3-Mus musculus
5GPR0165Gbeta-4-Mus musculus
6GPR0168Gbeta-5-Mus musculus-2
7GPR0291unclassified_Gbeta-Mus musculus-1
8GPR0318unclassified_Gbeta-Mus musculus-2
9GPR0376Gbeta-5-Mus musculus-3
10GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 11031246
11GPR0178Ggamma-t1-Mus musculus
12GPR0181Ggamma-2-Mus musculus
13GPR0184Ggamma-3-Mus musculus
14GPR0186Ggamma-4-Mus musculus
15GPR0189Ggamma-5-Mus musculus
16GPR0193Ggamma-7-Mus musculus
17GPR0196Ggamma-8-Mus musculus-2
18GPR0200Ggamma-11-Mus musculus
19GPR0204Ggamma-12-Mus musculus
20GPR0206Ggamma-13-Mus musculus
21GPR0211Ggamma-8-Mus musculus-1
22GPR0349Ggamma-1-Mus musculus
23GPR0379Ggamma-10-Mus musculus


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athina University of Athens
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