gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0337 ::
FAMILY Ezrin-radixin-moesin-binding phosphoproteins
SUBFAMILY Ezrin-radixin-moesin-binding phosphoproteins
TYPE EBP50/NHERF 1

Cross References:
UniProt P70441 | Q8BYD8 EMBL U74079 | AK040371 | BC085141
InterPro IPR015098 | IPR001478
GENEID 26941
PFAM PF09007 | PF00595

Details:
NAME EBP50/NHERF-1-Mus musculus-2
DESCRIPTION Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+)exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor ofNa(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1)(Solute carrier family 9 isoform A3 regulatory fac
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Slc9a3r1 | Nherf
SEQUENCE
MSADAAAGEPLPRLCCLEKGPNGYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLV
EVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDERLKKLGVSIREELLRPQEKSEQA
EPPAAADTHEAGDQNEAEKSHLRELRPRLCTMKKGPNGYGFNLHSDKSKPGQFIRAVDPD
SPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIKGGGDEAKLLVVDKETDEFFKKCKVI
PSQEHLDGPLPEPFS
FRAGMENT NO
FUNCTION Scaffold protein that connects plasma membrane proteinss with members of the ezrin/moesin/radixin family and thereby helpss to link them to the actin cytoskeleton and to regulate theirs surface expression
Interacting with G-proteins:
Family:Gq/11 REFERENCES:16182515
1GPR0240Galpha-q-Mus musculus


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