Details: |
NAME |
GRK2-Bos taurus |
DESCRIPTION |
Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G-protein-coupled receptor kinase 2). |
SPECIES |
Bos taurus |
COMMON NAME |
Bovine |
NCBI Taxonomy |
9913 |
GENE |
ADRBK1 | GRK2 |
SEQUENCE |
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS QKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMKELLAC SHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER IMLSLVSTGDCPFIV
|
FRAGMENT |
NO
|
FUNCTION |
Specifically phosphorylates the agonist-occupied form ofs the beta-adrenergic and closely related receptors, probablys inducing a desensitization of them |
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