gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0381 ::
FAMILY Ser Thr protein kinases
SUBFAMILY G protein coupled receptor kinases
TYPE GRK6

Cross References:
UniProt P97711 EMBL Y09365
InterPro IPR000239 | IPR000961 | IPR000719 | IPR000342 | IPR008271 | IPR002290
PRODOM PD000001
PRINTS PR00717 PFAM PF00069 | PF00615

Details:
NAME GRK6-Rattus norvegicus-4
DESCRIPTION G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupledreceptor kinase GRK6).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Grk6 | Gprk6
SEQUENCE
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
PIGRLLFREFCATRPELTRCTAFLDGVAEYEVTPDEKRKACGCRLMQNFLSHTGPDLIPE
VPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSMAPFADYLDSIYFNRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
VNSRFVVSLAYAYET
FRAGMENT NO
FUNCTION Specifically phosphorylates the activated forms of Gs protein-coupled receptors (By similarity)
Interacting with G-proteins:
Family:Gq/11 REFERENCES:14654303
1GPR0045Galpha-15-Rattus norvegicus


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