gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0398 ::
FAMILY Ion channels
SUBFAMILY Inwar rectifier K channels
TYPE Kir 3 1(GIRK1)

Cross References:
UniProt P48549 | Q8TBI0 EMBL U39196 | U50964 | BC022495
InterPro IPR001838 | IPR003274 | IPR013521 | IPR013518
PRODOM PD001103 GENEID 3760 MIM 601534
PRINTS PR01327 | PR01320 PFAM PF01007

Details:
NAME Kir 3.1(GIRK1)-Homo sapiens-2
DESCRIPTION G protein-activated inward rectifier potassium channel 1 (GIRK1)(Potassium channel, inwardly rectifying subfamily J member 3) (Inwardrectifier K(+) channel Kir3.1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE KCNJ3 | GIRK1
SEQUENCE 
MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNL
GSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNY
TPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCM
FIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE
GEFLPLDQLELDVGF
 FRAGMENT NO
FUNCTION This potassium channel is controlled by G proteins
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 14963032 | 11779482
1GPR0109Galpha-i3-Homo sapiens
2GPR0218Galpha-i1-Homo sapiens-1
3GPR0226Galpha-i2-Homo sapiens-2
4GPR0261Galpha-i1-Homo sapiens-2
5GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:12661754
6GPR0002Galpha-q-Homo sapiens-2
7GPR0237Galpha-q-Homo sapiens-1
Family:Gbeta REFERENCES:15251227 | 10944236 | 12661754
8GPR0147Gbeta-1-Homo sapiens
9GPR0155Gbeta-2-Homo sapiens
10GPR0160Gbeta-3-Homo sapiens-1
11GPR0164Gbeta-4-Homo sapiens
12GPR0167Gbeta-5-Homo sapiens-2
13GPR0363Gbeta-3-Homo sapiens-2
14GPR0366Gbeta-5-Homo sapiens-1
15GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227 | 10944236 | 12661754
16GPR0176Ggamma-t1-Homo sapiens
17GPR0179Ggamma-2-Homo sapiens
18GPR0183Ggamma-3-Homo sapiens
19GPR0185Ggamma-4-Homo sapiens
20GPR0188Ggamma-5-Homo sapiens-2
21GPR0192Ggamma-7-Homo sapiens
22GPR0195Ggamma-8-Homo sapiens-2
23GPR0198Ggamma-10-Homo sapiens-2
24GPR0199Ggamma-11-Homo sapiens
25GPR0203Ggamma-12-Homo sapiens
26GPR0205Ggamma-13-Homo sapiens
27GPR0210Ggamma-8-Homo sapiens-1
28GPR0253Ggamma-5-Homo sapiens-1
29GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory