gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0428 ::
FAMILY Ion channels
SUBFAMILY Inwar rectifier K channels
TYPE Kir 3 4(GIRK4)

Cross References:
UniProt P48545 | P97508 EMBL U33631 | AF403131
InterPro IPR001838 | IPR003277 | IPR013521 | IPR013518
PRODOM PD001103
PRINTS PR01330 | PR01320 PFAM PF01007

Details:
NAME Kir 3.4(GIRK4)-Mus musculus-2
DESCRIPTION G protein-activated inward rectifier potassium channel 4 (GIRK4)(Potassium channel, inwardly rectifying subfamily J member 5) (Inwardrectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiacinward rectifier) (CIR).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Kcnj5 | Girk4
SEQUENCE 
MAGDSRNAMNQDMEIGVTSQDHKKIPKQARDYIPIATDRTRLLTEGKKPRQRYMEKTGKC
NVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTITWLFFGFIWWLIAYVRGDLDH
VGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQPILGSIVNA
FMVGCMFVKISQPKKRAETLMFSNNAVISMRDENLCLMFRVGDLRNSHIVEASIRAKLIK
SRQTKEGEFIPLNQT
 FRAGMENT NO
FUNCTION This potassium channel is controlled by G proteins
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 14963032 | 11779482
1GPR0227Galpha-i2-Mus musculus-2
2GPR0289Galpha-i1-Mus musculus
3GPR0331Galpha-i2-Mus musculus-1
4GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:12661754
5GPR0240Galpha-q-Mus musculus
Family:Gbeta REFERENCES:15251227 | 10944236 | 12661754
6GPR0148Gbeta-1-Mus musculus
7GPR0156Gbeta-2-Mus musculus
8GPR0161Gbeta-3-Mus musculus
9GPR0165Gbeta-4-Mus musculus
10GPR0168Gbeta-5-Mus musculus-2
11GPR0291unclassified_Gbeta-Mus musculus-1
12GPR0318unclassified_Gbeta-Mus musculus-2
13GPR0376Gbeta-5-Mus musculus-3
14GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 10944236
15GPR0178Ggamma-t1-Mus musculus
16GPR0181Ggamma-2-Mus musculus
17GPR0184Ggamma-3-Mus musculus
18GPR0186Ggamma-4-Mus musculus
19GPR0189Ggamma-5-Mus musculus
20GPR0193Ggamma-7-Mus musculus
21GPR0196Ggamma-8-Mus musculus-2
22GPR0200Ggamma-11-Mus musculus
23GPR0204Ggamma-12-Mus musculus
24GPR0206Ggamma-13-Mus musculus
25GPR0211Ggamma-8-Mus musculus-1
26GPR0349Ggamma-1-Mus musculus
27GPR0379Ggamma-10-Mus musculus

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