gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0467 ::
FAMILY Phosphodiesterases
SUBFAMILY Rhodopsin-sensitive cGMP-specific PDEases
TYPE Phosphodiesterase 6

Cross References:
UniProt P11541 EMBL X12756 | M27541 | M36683 | M26043
InterPro IPR003018 | IPR003607 | IPR002073
GENEID 281973
PRINTS PR00387 PFAM PF01590 | PF00233

Details:
NAME Phosphodiesterase-6-Bos taurus-3
DESCRIPTION Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(EC 3.1.4.35) (GMP-PDE alpha) (PDE V-B1).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE PDE6A | PDEA
SEQUENCE
MGEVTAEEVEKFLDSNVSFAKQYYNLRYRAKVISDLLGPREAAVDFSNYHALNSVEESEI
IFDLLRDFQDNLQAEKCVFNVMKKLCFLLQADRMSLFMYRARNGIAELATRLFNVHKDAV
LEECLVAPDSEIVFPLDMGVVGHVALSKKIVNVPNTEEDEHFCDFVDTLTEYQTKNILAS
PIMNGKDVVAIIMVVNKVDGPHFTENDEEILLKYLNFANLIMKVFHLSYLHNCETRRGQI
LLWSGSKVFEELTDI
FRAGMENT NO
FUNCTION This protein participates in processes of transmissions and amplification of the visual signal
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 15988071 | 14699118
1GPR0245Galpha-t1-Bos taurus
2GPR0249Galpha-t2-Bos taurus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory