gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0489 ::
FAMILY Phosphodiesterases
SUBFAMILY Rhodopsin-sensitive cGMP-specific PDEases
TYPE Phosphodiesterase 6

Cross References:
UniProt P18545 | Q3KP63 EMBL M36476 | X62025 | U00482 | U00481 | BC106884
InterPro IPR006952
GENEID 5148 MIM 180073
PFAM PF04868

Details:
NAME Phosphodiesterase-6-Homo sapiens-4
DESCRIPTION Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterasesubunit gamma (EC 3.1.4.17) (GMP-PDE gamma).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE PDE6G | PDEG
SEQUENCE
MNLEPPKAEFRSATRVAGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGL
GTDITVICPWEAFNHLELHELAQYGII
FRAGMENT NO
FUNCTION Participates in processes of transmission ands amplification of the visual signal
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 15988071 | 14699118
1GPR0247Galpha-t1-Homo sapiens
2GPR0250Galpha-t2-Homo sapiens
3GPR0279Galpha-t-Homo sapiens


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athina University of Athens
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