gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0595 ::
FAMILY Ser Thr protein kinases
SUBFAMILY Protein kinases C(PKC)
TYPE Protein kinase D

Cross References:
UniProt Q15139 EMBL X75756
InterPro IPR002219 | IPR001849 | IPR011993 | IPR015727 | IPR000719 | IPR008271 | IPR002290
PRODOM PD000001 MIM 605435
PRINTS PR00008 PFAM PF00130 | PF00169 | PF00069

Details:
NAME Protein kinase D-Homo sapiens
DESCRIPTION Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Proteinkinase D) (Protein kinase C mu type) (nPKC-mu).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE PRKD1 | PKD | PKD1 | PRKCM
SEQUENCE 
MSAPPVLRPPSPLLPVAAAAAAAAAALVPGSGPGPAPFLAPVAAPVGGISFHLQIGLSRE
PVLLLQDSSGDYSLAHVREMACSIVDQKFPECGFYGMYDKILLFRHDPTSENILQLVKAA
SDIQEGDLIEVVLSRSATFEDFQIRPHALFVHSYRAPAFCDHCGEMLWGLVRQGLKCEGC
GLNYHKRCAFKIPNNCSGVRRRRLSNVSLTGVSTIRTSSAELSTSAPDEPLLQKSPSESF
IGREKRSNSQSYIGR
 FRAGMENT NO
FUNCTION This is calcium-independent, phospholipid-dependent,s serine- and threonine-specific enzyme
Interacting with G-proteins:
Family:G12/13 REFERENCES:11507098
1GPR0037Galpha-13-Homo sapiens
Family:Gq/11 REFERENCES:10636921
2GPR0002Galpha-q-Homo sapiens-2
3GPR0237Galpha-q-Homo sapiens-1
Family:Gbeta REFERENCES:15251227
4GPR0147Gbeta-1-Homo sapiens
5GPR0155Gbeta-2-Homo sapiens
6GPR0160Gbeta-3-Homo sapiens-1
7GPR0164Gbeta-4-Homo sapiens
8GPR0167Gbeta-5-Homo sapiens-2
9GPR0363Gbeta-3-Homo sapiens-2
10GPR0366Gbeta-5-Homo sapiens-1
11GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227
12GPR0176Ggamma-t1-Homo sapiens
13GPR0179Ggamma-2-Homo sapiens
14GPR0183Ggamma-3-Homo sapiens
15GPR0185Ggamma-4-Homo sapiens
16GPR0188Ggamma-5-Homo sapiens-2
17GPR0192Ggamma-7-Homo sapiens
18GPR0195Ggamma-8-Homo sapiens-2
19GPR0198Ggamma-10-Homo sapiens-2
20GPR0199Ggamma-11-Homo sapiens
21GPR0203Ggamma-12-Homo sapiens
22GPR0205Ggamma-13-Homo sapiens
23GPR0210Ggamma-8-Homo sapiens-1
24GPR0253Ggamma-5-Homo sapiens-1
25GPR0364Ggamma-10-Homo sapiens-1

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