gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0619 ::
FAMILY Small GTP-binding proteins
SUBFAMILY Rho small GTPases
TYPE Rac

Cross References:
UniProt P62999 | O95501 | P15154 | Q9BTB4 EMBL X56390
InterPro IPR003578 | IPR013753 | IPR001806 | IPR005225
GENEID 403955
PRINTS PR00449 PFAM PF00071

Details:
NAME Rac-Canis familiaris
DESCRIPTION Ras-related C3 botulinum toxin substrate 1 precursor (p21-Rac1)(Rac2).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE RAC1
SEQUENCE
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
FRAGMENT NO
FUNCTION Plasma membrane-associated small GTPase which cycless between active GTP-bound and inactive GDP-bound states
Interacting with G-proteins:
Family:Gi/o REFERENCES:11099498
1GPR0223Galpha-i2-Canis familiaris
Family:Gbeta REFERENCES:11099498 | 15251227
2GPR0146Gbeta-1-Canis familiaris
3GPR0159Gbeta-3-Canis familiaris
Family:Ggamma REFERENCES:11099498 | 15251227
4GPR0177Ggamma-t1-Canis familiaris


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory