gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0643 ::
FAMILY Small GTP-binding proteins
SUBFAMILY Rho small GTPases
TYPE Rac

Cross References:
UniProt P60763 | O14658 | Q5U0M8 EMBL AF008591 | AF498966 | BT019443 | BC009605 | BC015197
InterPro IPR003578 | IPR013753 | IPR001806 | IPR005225 PDB 2C2H | 2G0N | 2IC5 | 2OV2 | 2QME
GENEID 5881 MIM 602050
PRINTS PR00449 PFAM PF00071

Details:
NAME Rac-Homo sapiens-3
DESCRIPTION Ras-related C3 botulinum toxin substrate 3 precursor (p21-Rac3).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE RAC3
SEQUENCE 
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLR
DDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKPGKKCTVF
 FRAGMENT NO
FUNCTION Plasma membrane-associated small GTPase which cycless between an active GTP-bound and inactive GDP-bound state
Interacting with G-proteins:
Family:Gi/o REFERENCES:11099498
1GPR0109Galpha-i3-Homo sapiens
2GPR0218Galpha-i1-Homo sapiens-1
3GPR0226Galpha-i2-Homo sapiens-2
4GPR0261Galpha-i1-Homo sapiens-2
5GPR0365Galpha-i2-Homo sapiens-1
Family:Gbeta REFERENCES:11099498 | 15251227
6GPR0147Gbeta-1-Homo sapiens
7GPR0155Gbeta-2-Homo sapiens
8GPR0160Gbeta-3-Homo sapiens-1
9GPR0164Gbeta-4-Homo sapiens
10GPR0167Gbeta-5-Homo sapiens-2
11GPR0363Gbeta-3-Homo sapiens-2
12GPR0366Gbeta-5-Homo sapiens-1
13GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:11099498 | 15251227
14GPR0176Ggamma-t1-Homo sapiens
15GPR0179Ggamma-2-Homo sapiens
16GPR0183Ggamma-3-Homo sapiens
17GPR0185Ggamma-4-Homo sapiens
18GPR0188Ggamma-5-Homo sapiens-2
19GPR0192Ggamma-7-Homo sapiens
20GPR0195Ggamma-8-Homo sapiens-2
21GPR0198Ggamma-10-Homo sapiens-2
22GPR0199Ggamma-11-Homo sapiens
23GPR0203Ggamma-12-Homo sapiens
24GPR0205Ggamma-13-Homo sapiens
25GPR0210Ggamma-8-Homo sapiens-1
26GPR0253Ggamma-5-Homo sapiens-1
27GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
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