gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0068 ::
FAMILY Ion channels
SUBFAMILY ATP-sensitive inward rectifier potassium channels
TYPE ATP-sensitive inward rectifier potassium channel 1

Cross References:
UniProt O88335 EMBL AF012834 | BC020525
InterPro IPR001838 | IPR003268 | IPR013521 | IPR013518
PRODOM PD001103 GENEID 56379
PRINTS PR01321 | PR01320 PFAM PF01007

Details:
NAME ATP-sensitive inward rectifier potassium channel-1-Mus musculus
DESCRIPTION ATP-sensitive inward rectifier potassium channel 1 (Potassium channel,inwardly rectifying subfamily J member 1) (ATP-regulated potassiumchannel ROM-K) (Kir1.1).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Kcnj1
SEQUENCE 
MFKHLRRWFVTHIFGRSRQRARLVSKDGRCNIEFGNVDAQSRFIFFVDIWTTVLDLKWRY
KMTVFITAFLGSWFLFGLLWYVVAYVHKDLPEFYPPDNRTPCVENINGMTSAFLFSLETQ
VTIGYGFRFVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAV
ISKRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTITPEGETIILDQTNINFVVDAGNEN
LFFISPLTIYHIIDH
 FRAGMENT NO
FUNCTION In the kidney, probably plays a major role in potassiums homeostasis
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 10990455
1GPR0148Gbeta-1-Mus musculus
2GPR0156Gbeta-2-Mus musculus
3GPR0161Gbeta-3-Mus musculus
4GPR0165Gbeta-4-Mus musculus
5GPR0168Gbeta-5-Mus musculus-2
6GPR0291unclassified_Gbeta-Mus musculus-1
7GPR0318unclassified_Gbeta-Mus musculus-2
8GPR0376Gbeta-5-Mus musculus-3
9GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 10990455
10GPR0178Ggamma-t1-Mus musculus
11GPR0181Ggamma-2-Mus musculus
12GPR0184Ggamma-3-Mus musculus
13GPR0186Ggamma-4-Mus musculus
14GPR0189Ggamma-5-Mus musculus
15GPR0193Ggamma-7-Mus musculus
16GPR0196Ggamma-8-Mus musculus-2
17GPR0200Ggamma-11-Mus musculus
18GPR0204Ggamma-12-Mus musculus
19GPR0206Ggamma-13-Mus musculus
20GPR0211Ggamma-8-Mus musculus-1
21GPR0349Ggamma-1-Mus musculus
22GPR0379Ggamma-10-Mus musculus

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