gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0682 ::
FAMILY Ser Thr protein kinases
SUBFAMILY RAF protein kinases
TYPE Raf1 protein kinase

Cross References:
UniProt P04049 EMBL X03484 | AY271661 | BC018119
InterPro IPR002219 | IPR000719 | IPR003116 | IPR008271 PDB 1C1Y | 1FAQ | 1FAR | 1GUA | 1RFA
PRODOM PD000001 GENEID 5894 MIM 164760 | 611553 | 611554
PRINTS PR00008 PFAM PF00130 | PF00069 | PF02196

Details:
NAME Raf1 protein kinase-Homo sapiens-2
DESCRIPTION RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf-1) (C-RAF) (cRaf).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE RAF1 | RAF
SEQUENCE 
MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQ
 FRAGMENT NO
FUNCTION Involved in the transduction of mitogenic signals froms the cell membrane to the nucleus
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227
1GPR0147Gbeta-1-Homo sapiens
2GPR0155Gbeta-2-Homo sapiens
3GPR0160Gbeta-3-Homo sapiens-1
4GPR0164Gbeta-4-Homo sapiens
5GPR0167Gbeta-5-Homo sapiens-2
6GPR0363Gbeta-3-Homo sapiens-2
7GPR0366Gbeta-5-Homo sapiens-1
8GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227
9GPR0176Ggamma-t1-Homo sapiens
10GPR0179Ggamma-2-Homo sapiens
11GPR0183Ggamma-3-Homo sapiens
12GPR0185Ggamma-4-Homo sapiens
13GPR0188Ggamma-5-Homo sapiens-2
14GPR0192Ggamma-7-Homo sapiens
15GPR0195Ggamma-8-Homo sapiens-2
16GPR0198Ggamma-10-Homo sapiens-2
17GPR0199Ggamma-11-Homo sapiens
18GPR0203Ggamma-12-Homo sapiens
19GPR0205Ggamma-13-Homo sapiens
20GPR0210Ggamma-8-Homo sapiens-1
21GPR0253Ggamma-5-Homo sapiens-1
22GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
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