gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0727 ::
FAMILY Small GTP-binding proteins
SUBFAMILY Rho small GTPases
TYPE Rho

Cross References:
UniProt P24406 EMBL X56391
InterPro IPR003578 | IPR013753 | IPR001806 | IPR005225
GENEID 403954
PRINTS PR00449 PFAM PF00071

Details:
NAME Rho-Canis familiaris
DESCRIPTION Transforming protein RhoA precursor (Rho1).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE RHOA | ARHA | RHO1
SEQUENCE
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPTEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
FRAGMENT NO
FUNCTION Regulates a signal transduction pathway linking plasmas membrane receptors to the assembly of focal adhesions and actins stress fibers
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227
1GPR0146Gbeta-1-Canis familiaris
2GPR0159Gbeta-3-Canis familiaris
Family:Ggamma REFERENCES:15251227
3GPR0177Ggamma-t1-Canis familiaris


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