gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0755 ::
FAMILY Small GTP-binding proteins
SUBFAMILY Rho small GTPases
TYPE Rho

Cross References:
UniProt P61587 | P52199 EMBL X95282 | X97758 | AF498969 | BT006769 | BC012513 | S82240
InterPro IPR003578 | IPR013753 | IPR001806 | IPR005225 PDB 1M7B
GENEID 390 MIM 602924
PRINTS PR00449 PFAM PF00071

Details:
NAME Rho-Homo sapiens-8
DESCRIPTION Rho-related GTP-binding protein RhoE precursor (Rho family GTPase 3)(Rnd3) (Rho8) (MemB protein).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE RND3 | ARHE | RHO8 | RHOE
SEQUENCE 
MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
CTVM
 FRAGMENT NO
FUNCTION Binds GTP but lacks intrinsic GTPase activity and iss resistant to Rho-specific GTPase-activating proteins
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227
1GPR0147Gbeta-1-Homo sapiens
2GPR0155Gbeta-2-Homo sapiens
3GPR0160Gbeta-3-Homo sapiens-1
4GPR0164Gbeta-4-Homo sapiens
5GPR0167Gbeta-5-Homo sapiens-2
6GPR0363Gbeta-3-Homo sapiens-2
7GPR0366Gbeta-5-Homo sapiens-1
8GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227
9GPR0176Ggamma-t1-Homo sapiens
10GPR0179Ggamma-2-Homo sapiens
11GPR0183Ggamma-3-Homo sapiens
12GPR0185Ggamma-4-Homo sapiens
13GPR0188Ggamma-5-Homo sapiens-2
14GPR0192Ggamma-7-Homo sapiens
15GPR0195Ggamma-8-Homo sapiens-2
16GPR0198Ggamma-10-Homo sapiens-2
17GPR0199Ggamma-11-Homo sapiens
18GPR0203Ggamma-12-Homo sapiens
19GPR0205Ggamma-13-Homo sapiens
20GPR0210Ggamma-8-Homo sapiens-1
21GPR0253Ggamma-5-Homo sapiens-1
22GPR0364Ggamma-10-Homo sapiens-1

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