gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0756 ::
FAMILY Small GTP-binding proteins
SUBFAMILY Rho small GTPases
TYPE Rho

Cross References:
UniProt P62745 | P01121 | Q5U0H6 | Q7RTN5 | Q7RTR9 | Q9CUV7 EMBL X06820 | AF498971 | CR542272 | BT019546 | BT019547 | AC023137 | BC066954 | M12174 | BK001232 | BK001671
InterPro IPR003578 | IPR013753 | IPR001806 | IPR005225 PDB 2FV8
GENEID 388 MIM 165370
PRINTS PR00449 PFAM PF00071

Details:
NAME Rho-Homo sapiens-9
DESCRIPTION Rho-related GTP-binding protein RhoB precursor (H6).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE RHOB | ARH6 | ARHB
SEQUENCE 
MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
KRYGSQNGCINCCKVL
 FRAGMENT NO
FUNCTION Mediates apoptosis in neoplastically transformed cellss after DNA damage
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227
1GPR0147Gbeta-1-Homo sapiens
2GPR0155Gbeta-2-Homo sapiens
3GPR0160Gbeta-3-Homo sapiens-1
4GPR0164Gbeta-4-Homo sapiens
5GPR0167Gbeta-5-Homo sapiens-2
6GPR0363Gbeta-3-Homo sapiens-2
7GPR0366Gbeta-5-Homo sapiens-1
8GPR0402unclassified_Gbeta-Homo sapiens
Family:Ggamma REFERENCES:15251227
9GPR0176Ggamma-t1-Homo sapiens
10GPR0179Ggamma-2-Homo sapiens
11GPR0183Ggamma-3-Homo sapiens
12GPR0185Ggamma-4-Homo sapiens
13GPR0188Ggamma-5-Homo sapiens-2
14GPR0192Ggamma-7-Homo sapiens
15GPR0195Ggamma-8-Homo sapiens-2
16GPR0198Ggamma-10-Homo sapiens-2
17GPR0199Ggamma-11-Homo sapiens
18GPR0203Ggamma-12-Homo sapiens
19GPR0205Ggamma-13-Homo sapiens
20GPR0210Ggamma-8-Homo sapiens-1
21GPR0253Ggamma-5-Homo sapiens-1
22GPR0364Ggamma-10-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory