gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0798 ::
FAMILY Small GTP-binding proteins
SUBFAMILY Rho small GTPases
TYPE Rho

Cross References:
UniProt P61589 EMBL AY026068 | AY026069 | BC061732
InterPro IPR003578 | IPR013753 | IPR001806 | IPR005225
GENEID 117273
PRINTS PR00449 PFAM PF00071

Details:
NAME Rho-Rattus norvegicus-3
DESCRIPTION Transforming protein RhoA precursor.
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Rhoa | Arha | Arha2
SEQUENCE
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLIL
FRAGMENT NO
FUNCTION Regulates a signal transduction pathway linking plasmas membrane receptors to the assembly of focal adhesions and actins stress fibers
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227
1GPR0149Gbeta-1-Rattus norvegicus-2
2GPR0157Gbeta-2-Rattus norvegicus-2
3GPR0162Gbeta-3-Rattus norvegicus
4GPR0166Gbeta-4-Rattus norvegicus
5GPR0169Gbeta-5-Rattus norvegicus
6GPR0396Gbeta-2-Rattus norvegicus-1
7GPR0397Gbeta-1-Rattus norvegicus-1
Family:Ggamma REFERENCES:15251227
8GPR0190Ggamma-5-Rattus norvegicus
9GPR0194Ggamma-7-Rattus norvegicus
10GPR0197Ggamma-8-Rattus norvegicus
11GPR0201Ggamma-11-Rattus norvegicus
12GPR0256Ggamma-2-Rattus norvegicus
13GPR0257Ggamma-3-Rattus norvegicus
14GPR0258Ggamma-4-Rattus norvegicus
15GPR0259Ggamma-10-Rattus norvegicus
16GPR0260Ggamma-12-Rattus norvegicus


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