gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0836 ::
FAMILY SHC transforming proteins
SUBFAMILY SHC transforming proteins
TYPE SHC transforming protein 2

Cross References:
UniProt Q8BMC3 EMBL AK032878
InterPro IPR011993 | IPR006019 | IPR006020 | IPR000980
PRODOM PD000093
PRINTS PR00401 | PR00629 PFAM PF00640 | PF00017

Details:
NAME SHC transforming protein-2-Mus musculus-1
DESCRIPTION SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2domain-containing-transforming protein C2) (Protein Sck) (ProteinSli).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Shc2 | Sck | ShcB
SEQUENCE 
MPQWKFAAPGSFLGRGPAATRVAGVAEAQPEPGVPALAAVLGACEPRCAAPCPLPALGRC
RGSGTRGARVTPDVADEWVRKGGFIHKPAHGWLHPDARVLGPGVSYIVRYMGCIEVLRSM
RSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAPNKALASILGKSNLRFAGMSISVNIS
VDGLNLSVPATRQIIANHHMQSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLA
QSVISTVGQAFELRF
 FRAGMENT NO
FUNCTION Signaling adapter that couples activated growth factors receptors to signaling pathway in neurons
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 14671004 | 7568118
1GPR0148Gbeta-1-Mus musculus
2GPR0156Gbeta-2-Mus musculus
3GPR0161Gbeta-3-Mus musculus
4GPR0165Gbeta-4-Mus musculus
5GPR0168Gbeta-5-Mus musculus-2
6GPR0291unclassified_Gbeta-Mus musculus-1
7GPR0318unclassified_Gbeta-Mus musculus-2
8GPR0376Gbeta-5-Mus musculus-3
9GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 14671004 | 7568118
10GPR0178Ggamma-t1-Mus musculus
11GPR0181Ggamma-2-Mus musculus
12GPR0184Ggamma-3-Mus musculus
13GPR0186Ggamma-4-Mus musculus
14GPR0189Ggamma-5-Mus musculus
15GPR0193Ggamma-7-Mus musculus
16GPR0196Ggamma-8-Mus musculus-2
17GPR0200Ggamma-11-Mus musculus
18GPR0204Ggamma-12-Mus musculus
19GPR0206Ggamma-13-Mus musculus
20GPR0211Ggamma-8-Mus musculus-1
21GPR0349Ggamma-1-Mus musculus
22GPR0379Ggamma-10-Mus musculus

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory