gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::Effector View
Entry 1 of 1 :: EFF0886 ::
FAMILY Tyr protein kinases
SUBFAMILY Tyr protein kinases
TYPE Tsk tyrosine kinase

Cross References:
UniProt Q03526 EMBL L00619 | L05631 | L10628 | D14042
InterPro IPR001562 | IPR001849 | IPR011993 | IPR000719 | IPR000980 | IPR001452 | IPR013315 | IPR001245 | IPR008266 PDB 1AWJ | 1LUI | 1LUK | 1LUM | 1LUN | 2ETZ | 2EU0
PRODOM PD000001 | PD000093 | PD000066
PRINTS PR00401 | PR00452 | PR01887 | PR00402 | PR00109 PFAM PF00779 | PF00169 | PF07714 | PF00017 | PF00018

Details:
NAME Tsk tyrosine kinase-Mus musculus-2
DESCRIPTION Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase)(IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Itk | Emt | Tlk | Tsk
SEQUENCE
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRI
KCVEIVKSDISIPCHYKYPFQTLVYLQVVHDNYLLYVFAPDCESRQRWVLTLKEETRNNN
SLVSKYHPNFWMDGRWRCCSQLEKPAVGCAPYDPSKNASKKPLPPTPEDNRRSFQEPEET
LVIALYDYQTNDPQELALRCDEEYYLLDSSEIHWWRVQDKNGHEGYAPSSYLVEKSPNNL
ETYEWYNKSISRDKA
FRAGMENT NO
FUNCTION May play a role in T-cell development, potentially ins thymic selection
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 14671004
1GPR0148Gbeta-1-Mus musculus
2GPR0156Gbeta-2-Mus musculus
3GPR0161Gbeta-3-Mus musculus
4GPR0165Gbeta-4-Mus musculus
5GPR0168Gbeta-5-Mus musculus-2
6GPR0291unclassified_Gbeta-Mus musculus-1
7GPR0318unclassified_Gbeta-Mus musculus-2
8GPR0376Gbeta-5-Mus musculus-3
9GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 14671004
10GPR0178Ggamma-t1-Mus musculus
11GPR0181Ggamma-2-Mus musculus
12GPR0184Ggamma-3-Mus musculus
13GPR0186Ggamma-4-Mus musculus
14GPR0189Ggamma-5-Mus musculus
15GPR0193Ggamma-7-Mus musculus
16GPR0196Ggamma-8-Mus musculus-2
17GPR0200Ggamma-11-Mus musculus
18GPR0204Ggamma-12-Mus musculus
19GPR0206Ggamma-13-Mus musculus
20GPR0211Ggamma-8-Mus musculus-1
21GPR0349Ggamma-1-Mus musculus
22GPR0379Ggamma-10-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory