gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1112 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY SPC/LPC

Cross References:
UniProt Q15743 | Q13334 | Q6IX34 EMBL U35398 | U48405 | AY615372 | BC067472 | BC069592
InterPro IPR000276 | IPR005389 GPCRDB SPR1_HUMAN
MIM 601404
PRINTS PR00237 | PR01564 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_SPC/LPC_Homo sapiens-4
DESCRIPTION Sphingosylphosphorylcholine receptor (Ovarian cancer G-protein coupledreceptor 1) (OGR-1) (G-protein coupled receptor 68) (GPR12A).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE GPR68 | OGR1
SEQUENCE 
MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYL
CNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRY
LAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHRVCFEHYPIQA
WQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLAC
FLPYHVLLLVRSVWEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARL
RGACLAFLTCSRTGRAREAYPLGAPEASGKSGAQGEEPELLTKLHPAFQTPNSPGSGGFP
TGRLA
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:12069813
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory