gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1113 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY SPC/LPC

Cross References:
UniProt Q8IYL9 | O75819 EMBL U95218 | AL157955 | BC035633 | BC071715
InterPro IPR000276 | IPR005464 GPCRDB PSYR_HUMAN
GENEID 8477 MIM 604620
PRINTS PR00237 | PR01649 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_SPC/LPC_Homo sapiens-7
DESCRIPTION Psychosine receptor (G-protein coupled receptor 65) (T-cell death-associated protein 8).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE GPR65 | TDAG8
SEQUENCE
MNSTCIEEQHDLDHYLFPIVYIFVIIVSIPANIGSLCVSFLQAKKESELGIYLFSLSLSD
LLYALTLPLWIDYTWNKDNWTFSPALCKGSAFLMYMNFYSSTAFLTCIAVDRYLAVVYPL
KFFFLRTRRFALMVSLSIWILETIFNAVMLWEDETVVEYCDAEKSNFTLCYDKYPLEKWQ
INLNLFRTCTGYAIPLVTILICNRKVYQAVRHNKATENKEKKRIIKLLVSITVTFVLCFT
PFHVMLLIRCILEHAVNFEDHSNSGKRTYTMYRITVALTSLNCVADPILYCFVTETGRYD
MWNILKFCTGRCNTSQRQRKRILSVSTKDTMELEVLE
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:12069813
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1


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athina University of Athens
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Biophysics
& Bioinformatics
Laboratory