gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1247 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY NEUROPEPTIDE Y RECEPTOR
SUBFAMILY Y1

Cross References:
UniProt Q9DDN6 EMBL AF309091
InterPro IPR000276 | IPR001358 | IPR000611 GPCRDB NPY2R_CHICK
GENEID 422405
PRINTS PR00237 | PR01014 | PR01012 PFAM PF00001

Details:
NAME NEUROPEPTIDE Y RECEPTOR_Y1_Gallus gallus-1
DESCRIPTION Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor).
SPECIES Gallus gallus COMMON NAME Chicken NCBI Taxonomy 9031
GENE NPY2R
SEQUENCE
MGPLEAIGEENQTDEMKMELFTKLYLPRYTTPVSELALDPKPELKDSTTLVEVQIILIFA
YCSIILLGVIGNSLVIHVIIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLVYTLLGEW
KLGPVLCHLVPYAQALAVHVSTVTLTVIALDRHRCIVYHLESKISKRISFLIIGVAWAVS
ALLASPLAIFREYSLIEIIPDFKIVVCSEKWPGEGQLNYGTIYSVSMLLIQYVLPLAIIS
YAYTRIWTKLKNHVSPGAGNDHYHHRRQKTTKMLVCVVVVFAVSWLPFHAFQLVSDIDSQ
VLDLKEYKLIYTVFHVIAMCSTFANPLLYGWMNNNYRTAFLTAFQCEQRLDSIHPEVSAA
FKARKKLEAKKSQFPGDSFTQPTNV
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12524448

Coupling with G-proteins:
Family:Gi/o REFERENCES:1321422
1GPR0217Galpha-i1-Gallus gallus
2GPR0225Galpha-i2-Gallus gallus
Family:Gq/11 REFERENCES:1321422
3GPR0003Galpha-11-Gallus gallus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory