gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1279 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY NICOTINIC ACID RECEPTOR
SUBFAMILY NICOTINIC ACID

Cross References:
UniProt Q8TDS4 | A0PJL5 | A7LGG3 EMBL AY148884 | AB083632 | AB065876 | EU012026 | BC027965 | BC056419
InterPro IPR000276 | IPR002286 GPCRDB G109A_HUMAN
GENEID 338442 MIM 609163
PRINTS PR00237 | PR01157 PFAM PF00001

Details:
NAME NICOTINIC ACID RECEPTOR_NICOTINIC ACID_Homo sapiens-1
DESCRIPTION Nicotinic acid receptor 1 (G-protein coupled receptor 109A) (G-proteincoupled receptor HM74A).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE GPR109A | HM74A
SEQUENCE 
MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK
SSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTV
VAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSF
SICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
VICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS
FPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGP
TSP
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:15183629 | 12563315
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
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