gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1281 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY NICOTINIC ACID RECEPTOR
SUBFAMILY NICOTINIC ACID

Cross References:
UniProt P49019 | A8K4G5 | Q8NGE4 EMBL D10923 | AB065865 | EU293604 | AK290930 | BC047891
InterPro IPR000276 | IPR002286 GPCRDB G109B_HUMAN
GENEID 8843 MIM 606039
PRINTS PR00237 | PR01157 PFAM PF00001

Details:
NAME NICOTINIC ACID RECEPTOR_NICOTINIC ACID_Homo sapiens-2
DESCRIPTION Nicotinic acid receptor 2 (G-protein coupled receptor 109B) (G-proteincoupled receptor HM74) (G-protein coupled receptor HM74B).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE GPR109B
SEQUENCE
MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK
SSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTV
VAVDRYFRVVHPHHALNKISNWTAAIISCLLWGITVGLTVHLLKKKLLIQNGPANVCISF
SICHTFRWHEAMFLLEFLLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
VICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS
FPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGP
TSNNHSKKGHCHQEPASLEKQLGCCIE
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:15183629 | 12563315
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1


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athina University of Athens
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