| Details: |
| NAME |
ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M2_Mus musculus |
| DESCRIPTION |
Muscarinic acetylcholine receptor M2. |
| SPECIES |
Mus musculus |
COMMON NAME |
Mouse |
NCBI Taxonomy |
10090 |
| GENE |
Chrm2 | Chrm-2 |
| SEQUENCE |
MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRI
VKPNNNNMPGGDGGLEHNKIQNGKALRDGGTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDDNSRQTCIKIVTKTQKGDACTPTSTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
|
FRAGMENT |
NO
|
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|
Homepage
|
| Dimerization: |
| HETERODIMER INFORMATION |
Forms heterodimers with Muscarinic M3 Receptors. Heterodimerization results in altered internalization of the receptors
|
METHOD |
Chimeric receptor reconstitution studies
|
REFERENCES |
10490911
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 3443095 | | 1 | GPR0021 | Galpha-o1-Mus musculus | | 2 | GPR0227 | Galpha-i2-Mus musculus-2 | | 3 | GPR0289 | Galpha-i1-Mus musculus | | 4 | GPR0331 | Galpha-i2-Mus musculus-1 | | 5 | GPR0385 | Galpha-i3-Mus musculus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
