Details: |
NAME |
ADENOSINE RECEPTOR_A1_Mus musculus-1 |
DESCRIPTION |
Adora1 protein . |
SPECIES |
Mus musculus |
COMMON NAME |
Mouse |
NCBI Taxonomy |
10090 |
GENE |
Adora1 |
SEQUENCE |
VLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTY FHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSL VVGLTPMFGWNNLSEVEQAWIANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLM VLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCI TLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIE EDIPEEKADD
|
FRAGMENT |
YES
|
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Homepage
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Dimerization: |
HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12123822
|
HETERODIMER INFORMATION |
Forms heterodimers with Dopamine D1 Receptor. Heterodimerization results in altered D1 receptor signalling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10890919
|
HETERODIMER INFORMATION |
Forms heterodimers with Metabotropic Glutamate Receptor 1. Dimerization results in alteration of signalling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11278325
|
HETERODIMER INFORMATION |
Forms heterodimers with P2Y1 Receptors. Heterodimerization results in altered ligand binding
|
METHOD |
Immunoprecipitation, Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
11390975 | 12417330 | 12123822
|
Coupling with G-proteins: |
Family:Gi/o |
REFERENCES: | 1662665 | 1 | GPR0021 | Galpha-o1-Mus musculus | 2 | GPR0227 | Galpha-i2-Mus musculus-2 | 3 | GPR0289 | Galpha-i1-Mus musculus | 4 | GPR0331 | Galpha-i2-Mus musculus-1 | 5 | GPR0385 | Galpha-i3-Mus musculus |
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