| Details: |
| NAME |
ADENOSINE RECEPTOR_A1_Canis familiaris |
| DESCRIPTION |
Adenosine receptor A1. |
| SPECIES |
Canis familiaris |
COMMON NAME |
Dog |
NCBI Taxonomy |
9615 |
| GENE |
ADORA1 | RDC7 |
| SEQUENCE |
MPPAISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPRTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAAVAIAGCWILSFVVGLTPLFGWNRLGEAQRAWAANGSGGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRRQLGKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCRKPSILMYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPTPPVDEDPPEEAPHD
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12123822
|
| HETERODIMER INFORMATION |
Forms heterodimers with Dopamine D1 Receptor. Heterodimerization results in altered D1 receptor signalling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10890919
|
| HETERODIMER INFORMATION |
Forms heterodimers with Metabotropic Glutamate Receptor 1. Dimerization results in alteration of signalling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11278325
|
| HETERODIMER INFORMATION |
Forms heterodimers with P2Y1 Receptors. Heterodimerization results in altered ligand binding
|
METHOD |
Immunoprecipitation, Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
11390975 | 12417330 | 12123822
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 1662665 | | 1 | GPR0223 | Galpha-i2-Canis familiaris |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
