| Details: |
| NAME |
OPIOID AND OPIOID-LIKE RECEPTOR_KAPPA OPIOID PEPTIDE (KOR)_Homo sapiens |
| DESCRIPTION |
Kappa-type opioid receptor (KOR-1). |
| SPECIES |
Homo sapiens |
COMMON NAME |
Human |
NCBI Taxonomy |
9606 |
| GENE |
OPRK1 | OPRK |
| SEQUENCE |
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10385123
|
| HETERODIMER INFORMATION |
Forms heterodimers with delta Opioid Peptide Receptor. Dimerization results in altered ligand binding, potentiated signalling and altered internalization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10385123
|
| HETERODIMER INFORMATION |
Forms heterodimers with B2 Adrenoceptors. Heterodimerization results in altered internalization and MAPK signalling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11134510
|
| Scaffold: |
| TYPE |
NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein)
|
REFERENCES |
12004055
|
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
