| Details: |
| NAME |
OPIOID AND OPIOID-LIKE RECEPTOR_KAPPA OPIOID PEPTIDE (KOR)_Mus musculus-1 |
| DESCRIPTION |
Kappa-type opioid receptor (KOR-1) (MSL-1). |
| SPECIES |
Mus musculus |
COMMON NAME |
Mouse |
NCBI Taxonomy |
10090 |
| GENE |
Oprk1 |
| SEQUENCE |
MESPIQIFRGDPGPTCSPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLESAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10385123
|
| HETERODIMER INFORMATION |
Forms heterodimers with delta Opioid Peptide Receptor. Dimerization results in altered ligand binding, potentiated signalling and altered internalization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10385123
|
| HETERODIMER INFORMATION |
Forms heterodimers with B2 Adrenoceptors. Heterodimerization results in altered internalization and MAPK signalling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11134510
|
| Scaffold: |
| TYPE |
NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein)
|
REFERENCES |
12004055
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 7624359 | | 1 | GPR0021 | Galpha-o1-Mus musculus | | 2 | GPR0227 | Galpha-i2-Mus musculus-2 | | 3 | GPR0289 | Galpha-i1-Mus musculus | | 4 | GPR0331 | Galpha-i2-Mus musculus-1 | | 5 | GPR0385 | Galpha-i3-Mus musculus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
