gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1918 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY OPIOID AND OPIOID-LIKE RECEPTOR
SUBFAMILY N/OFQ RECEPTOR

Cross References:
UniProt P41146 | Q8WYH9 | Q9H4K4 EMBL X77130 | U30185 | AF348323 | AF126470 | AY268428 | AL121581 | BC038433 | L40949
InterPro IPR000276 | IPR001418 | IPR001420 GPCRDB OPRX_HUMAN
GENEID 4987 MIM 602548
PRINTS PR00237 | PR00384 | PR00547 PFAM PF00001

Details:
NAME OPIOID AND OPIOID-LIKE RECEPTOR_N/OFQ RECEPTOR_Homo sapiens
DESCRIPTION Nociceptin receptor (Orphanin FQ receptor) (Kappa-type 3 opioidreceptor) (KOR-3).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE OPRL1 | OOR | ORL1
SEQUENCE 
MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
KTSETVPRPA
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:15019559
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory