gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2379 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY P2Y RECEPTOR
SUBFAMILY P2Y1

Cross References:
UniProt P49652 EMBL U09842 | AF012103
InterPro IPR001277 | IPR000276 | IPR002286 | IPR000142 GPCRDB P2RY1_MELGA
PRINTS PR00645 | PR00237 | PR00595 | PR01157 PFAM PF00001

Details:
NAME P2Y RECEPTOR_P2Y1_Meleagris gallopavo
DESCRIPTION P2Y purinoceptor 1 (ATP receptor) (P2Y1) (Purinergic receptor) (6H1orphan receptor).
SPECIES Meleagris gallopavo COMMON NAME Common turkey NCBI Taxonomy 9103
GENE P2RY1
SEQUENCE 
MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSV
AIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIF
HVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSG
TGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDN
SPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRG
LASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDT
SL
 FRAGMENT NO

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Dimerization:
HETERODIMER INFORMATION Forms heterodimers with Adenosine A1 Receptor. Heterodimerization results in altered ligand binding METHOD Immunoprecipitation, Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 11390975 | 12417330 | 12123822

Scaffold:
TYPE NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein) REFERENCES 9671706

Coupling with G-proteins:
Family:Gq/11 REFERENCES:8159738
1GPR0030Galpha-11-Meleagris gallopavo

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