gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2383 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY P2Y RECEPTOR
SUBFAMILY P2Y12

Cross References:
UniProt Q9H244 | Q546J7 EMBL AF313449 | AF321815 | AB052684 | AF310685 | AJ320495 | AB083596 | AY136754 | BC017898
InterPro IPR000276 | IPR002286 | IPR005394 PDB 1T78 | 1VZ1 | 1Y9C GPCRDB P2Y12_HUMAN
GENEID 64805 MIM 600515 | 609821
PRINTS PR00237 | PR01569 | PR01157 PFAM PF00001

Details:
NAME P2Y RECEPTOR_P2Y12_Homo sapiens-1
DESCRIPTION P2Y purinoceptor 12 (P2Y12) (P2Y12 platelet ADP receptor) (P2Y(ADP))(ADP-glucose receptor) (ADPG-R) (P2Y(AC)) (P2Y(cyc)) (P2T(AC))(SP1999).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE P2RY12 | HORK3
SEQUENCE 
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI
IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI
DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS
EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI
IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF
LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11196645
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
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