gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0240 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADRENOCEPTOR (A2-ADRENOCEPTOR)
SUBFAMILY A2B(Adrenoceptor)

Cross References:
UniProt Q925K7 EMBL AF332049
InterPro IPR015695 | IPR000207 | IPR002233 | IPR000276 GPCRDB Q925K7_MOUSE
PRINTS PR01103 | PR00559 | PR00237 PFAM PF00001

Details:
NAME ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2B(Adrenoceptor)_Mus musculus-2
DESCRIPTION Adrenergic receptor alpha 2B.
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Adra2b
SEQUENCE
MVHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPHGLPQCELNQEAWYILASSIGS
FFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPRPAAGGVPASAKVPTLVSP
LSSVGEANGHPKPPREKEEGETPEDPEARALPPNWSALPRSVQDQKKGTSGATAEKGAEE
DEEEVEECEPQTLPASPASVFNPPLQQPQTSRVLATLRGQVLLSKNVGVASGQWWRRRTQ
LSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICPQHCKVPHGLFQFFFWIGYCNSSLN
PVIYTIFNQDFRRAFRRILCRQWTQTGW
FRAGMENT NO

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Scaffold:
TYPE 15-3-3 ksi REFERENCES 10224112
TYPE GASP( GPCR associated sorting protein) REFERENCES 12142540
TYPE Spinophilin/neurabin II REFERENCES 11154706

Coupling with G-proteins:
Family:Gi/o REFERENCES:2164221
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory