gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2415 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROLACTIN RELEASING PEPTIDE RECEPTOR (PRRPR)
SUBFAMILY PrRP

Cross References:
UniProt P49683 | O75194 | Q502U8 | Q5VXR9 EMBL U32672 | AB015745 | AB048946 | AL356865 | BC095539 | BC101490 | BC101492
InterPro IPR000276 | IPR001402 GPCRDB PRLHR_HUMAN
GENEID 2834 MIM 600895
PRINTS PR00237 | PR01018 PFAM PF00001

Details:
NAME PROLACTIN RELEASING PEPTIDE RECEPTOR (PRRPR)_PrRP_Homo sapiens
DESCRIPTION Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10) (hGR3).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE PRLHR | GPR10 | GR3
SEQUENCE
MASSTTRGPRVSDLFSGLPPAVTTPANQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLK
GLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAY
AFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAV
LAIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLV
ILLSYVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFCLLVVVVVVFAVCWLPLHVFNLL
RDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVAWPRKIAPH
GQNMTVSVVI
FRAGMENT NO

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Scaffold:
TYPE GRIP1( glutamate receptor interacting protein 1) REFERENCES 11641419
TYPE GRIP2 ( ABP) ( glutamate receptor interacting protein 2) REFERENCES 11641419
TYPE PICK1( protein interacting with protein kinase) REFERENCES
TYPE Shank3/ProSAP2( proline-rich synapse-associated protein 2) REFERENCES 11641419

Coupling with G-proteins:
Family:Gq/11 REFERENCES:11030716
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory