gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2458 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROTEASE-ACTIVATED RECEPTOR
SUBFAMILY PAR1

Cross References:
UniProt Q00991 | Q60461 EMBL X61958 | U34047
InterPro IPR000276 | IPR002286 | IPR000935 GPCRDB PAR1_CRILO
PRINTS PR00237 | PR01157 | PR00908 PFAM PF00001

Details:
NAME PROTEASE-ACTIVATED RECEPTOR_PAR1_Cricetulus longicaudatus
DESCRIPTION Proteinase-activated receptor 1 precursor (PAR-1) (Thrombin receptor).
SPECIES Cricetulus longicaudatus COMMON NAME Long-tailed hamster NCBI Taxonomy 10030
GENE F2R | PAR1
SEQUENCE
MGPQRLLLVAAGLSLCGPLLSSRVPVRQPESEMTDATVNPRSFFLRNPGENTFELIPLGD
EEEKNESTLPEGRAIYLNKSHSPPAPLAPFISEDASGYLTSPWLRLFIPSVYTFVFVVSL
PLNILAIAVFVLKMKVKKPAVVYMLHLAMADVLFVSVLPLKISYYFSGSDWQFGSGMCRF
ATAAFYCNMYASIMLMTVISIDRFLAVVYPIQSLSWRTLGRANFTCLVIWVMAIMGVVPL
LLKEQTTRVPGLNITTCHDVLNETLLQGFYSYYFSAFSAVFFLVPLIISTICYMSIIRCL
SSSSVANRSKKSRALFLSAAVFCVFIVCFGPTNVLLIMHYLLLSDSPATEKAYFAYLLCV
CVSSVSCCIDPLIYYYASSECQRHLYGILCCKESSDPNSYNSTGQLMPSKMDTCSSHLNN
SIYKKLLA
FRAGMENT NO

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Scaffold:
TYPE SNX1( sorting nexin) REFERENCES 12058063

Coupling with G-proteins:
Family:Gi/o REFERENCES:10644723
1GPR0018Galpha-o1-Cricetulus longicaudatus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory