gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2472 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY SOMATOSTATIN RECEPTOR
SUBFAMILY SST1

Cross References:
UniProt Q9PVG0 EMBL AF097726
InterPro IPR000276 | IPR004047 | IPR000586 | IPR001116 GPCRDB Q9PVG0_CARAU
PRINTS PR00237 | PR01507 | PR00246 | PR00587 PFAM PF00001

Details:
NAME SOMATOSTATIN RECEPTOR_SST1_Carassius auratus-2
DESCRIPTION Somatostatin receptor type 1 subtype A.
SPECIES Carassius auratus COMMON NAME Goldfish NCBI Taxonomy 7957
GENE sst1A
SEQUENCE
MLPNDTFKNLEDGLYLINFSSNETHNGDSHGSSAIFISFIYSVVCLVGLCGNSMVIYVIF
RYAKMKTATNIYILNLAIADELLMLSVPFLVTSSLLHHWPFGSLLCRLVLSVDAINMFTS
IYCLTVLSIDRYISVVHPIKAARYRRPTIAKMVNLGVWMFSILVILPIIIFSTTAPNSDG
SVACNMQMPEPERQWMAVFVIYAFLMGFLFPVIAICMCYILIIVKMRVVALKAGWQQRKK
SERKITLMVMMVVTVFVICWMPFHIMQLVSVFVQQHNATLSQLAVILGYANSCANPILYG
FLSDNFRRSFQRILCLRWWDNATEEPIDYYATALKSRGYSVDDFQPENLESGSTYRNGTC
TSRTTTL
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation, Fluorescence Resonance Energy Transfer (FRET) REFERENCES 10713101
HETERODIMER INFORMATION Forms heterodimer with SST5 Receptor. Dimerization allows internalization of SST1 Receptor METHOD Photobleaching Fluorescence Resonance Energy Transfer (FRET) REFERENCES 10713101

Coupling with G-proteins:
No information


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory