gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2474 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY SOMATOSTATIN RECEPTOR
SUBFAMILY SST1

Cross References:
UniProt Q9GKP7 EMBL AF148990
InterPro IPR000276 | IPR000586 | IPR001116 GPCRDB Q9GKP7_PIG
PRINTS PR00237 | PR00246 | PR00587 PFAM PF00001

Details:
NAME SOMATOSTATIN RECEPTOR_SST1_Sus scrofa
DESCRIPTION Somatostatin receptor 1 .
SPECIES Sus scrofa COMMON NAME Pig NCBI Taxonomy 9823
GENE SSTR1
SEQUENCE
SPSPCPGSCGEXSGSRGPGAGTADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVG
LCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRL
VLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPI
VVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRM
VALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILG
YANSCANPILYGFLS
FRAGMENT YES

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation, Fluorescence Resonance Energy Transfer (FRET) REFERENCES 10713101
HETERODIMER INFORMATION Forms heterodimer with SST5 Receptor. Dimerization allows internalization of SST1 Receptor METHOD Photobleaching Fluorescence Resonance Energy Transfer (FRET) REFERENCES 10713101

Coupling with G-proteins:
No information


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory