gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2485 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY SOMATOSTATIN RECEPTOR
SUBFAMILY SST3

Cross References:
UniProt P30935 EMBL M91000
InterPro IPR000276 | IPR000586 | IPR001856 GPCRDB SSR3_MOUSE
PRINTS PR00237 | PR00246 | PR00589 PFAM PF00001

Details:
NAME SOMATOSTATIN RECEPTOR_SST3_Mus musculus
DESCRIPTION Somatostatin receptor type 3 (SS3R) (SSR-28).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Sstr3 | Smstr3
SEQUENCE
MATVTYPSSEPMTLDPGNTSSTWPLDTTLGNTSAGASLTGLAVSGILISLVYLVVCVVGL
LGNSLVIYVVLRHTSSPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLV
MAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSRAVWVASAVVVLPVV
VFSGVPRGMSTCHMQWPEPAAAWRTAFIIYMAALGFFGPLLVICLCYLLIVVKVRSTTRR
VRAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIVNVVCPLPEEPAF
FGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRIRSQEPGSGPPEKTEEE
EDEEEEERREEEERRMQRGQEMNGRLSQIAQAGTSGQQPRPCTGTAKEQQLLPQEATAGD
KASTLSHL
FRAGMENT NO

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Dimerization:
HETERODIMER INFORMATION Forms heterodimer with SST2 Receptor. Dimerization results in inactivation of SST3 Receptor function METHOD Immunoprecipitation REFERENCES 11134004

Coupling with G-proteins:
Family:Gi/o REFERENCES:1337145
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus


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Biophysics
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