| Details: |
| NAME |
SOMATOSTATIN RECEPTOR_SST5_Mus musculus-1 |
| DESCRIPTION |
Somatostatin subtype 5 receptor. |
| SPECIES |
Mus musculus |
COMMON NAME |
Mouse |
NCBI Taxonomy |
10090 |
| GENE |
Sstr5 |
| SEQUENCE |
MCPLVTPSSLAEIHVLWHPEPDSMEPLSLASTPSWNASAASSGSHNWSLVDPVSPMGARA
VLVPVLYLLVCTVGLGGNTLVIYVVLRYAKMKTVTNVYILNLAVADVLFMLGLPFLATQN
AVSYWPFGSFLCRLVMTLDGINQFTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKLAS
AAVWVFSLLMSLPLLVFADVQEGWGTCNLSWPEPVGLWGAAFITYTSVLGFFGPLLVICL
CYLLIVVKVKAAGMRVGSSRRRRSERKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPE
EPTSAGLYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKALCLRRGYGVEDADAIEPRPD
KSGRPQTTLPTRSCEANGLMQTSRL
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation, Fluorescence Resonance Energy Transfer (FRET)
|
REFERENCES |
10713101
|
| HETERODIMER INFORMATION |
Forms heterodimer with SST1 Receptor. Dimerization allows internalization of SST1 Receptor
|
METHOD |
Photobleaching Fluorescence Resonance Energy Transfer (FRET)
|
REFERENCES |
10713101
|
| HETERODIMER INFORMATION |
Forms heterodimer with Dopamine Receptor D2. Dimerization results in increased ligand binding affnity and enhanced signalling
|
METHOD |
Photobleaching Fluorescence Resonance Energy Transfer (FRET)
|
REFERENCES |
10753124
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 8373420 | | 1 | GPR0021 | Galpha-o1-Mus musculus | | 2 | GPR0227 | Galpha-i2-Mus musculus-2 | | 3 | GPR0289 | Galpha-i1-Mus musculus | | 4 | GPR0331 | Galpha-i2-Mus musculus-1 | | 5 | GPR0385 | Galpha-i3-Mus musculus |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
