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gpDB::GPCR View
Entry 1 of 1 :: GPCR0025 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-1B

Cross References:
UniProt P79250 | Q6VVV0 EMBL AY323909 | AB193090 | AY204572 | S82461
InterPro IPR002147 | IPR002231 | IPR000276 GPCRDB 5HT1B_CANFA
GENEID 403741
PRINTS PR00513 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-1B_Canis familiaris
DESCRIPTION 5-hydroxytryptamine receptor 1B (5-HT-1B) (Serotonin receptor 1B) (5-HT1B) (5-HTR1B) (5-HT1D subtype beta).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE HTR1B
SEQUENCE
MEAAGAPCAPPPPAGSQTGAPPANLSSAPHNCSAEGYIYQDSVALPWKVLLVILLALITL
ATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVV
CDLWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISIS
LPPFFWRQAKAEEEVSDCVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILK
QTPNRTGKRLTRAQLITDSPGSTSSVTSVNSRAPDVPSESGSPVYVNQVKVRVSDALLEK
KKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLN
SLINPIIYTMSNEDFKQAFHKLIRFKCAG
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 10452531
HETERODIMER INFORMATION Forms functional heterodimers when co-expressed with 5-HT-1D Receptor. METHOD Immunoprecipitation REFERENCES 10452531

Coupling with G-proteins:
Family:Gi/o REFERENCES:1351684
1GPR0223Galpha-i2-Canis familiaris


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory