gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2561 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY VASOPRESSIN AND OXYTOCIN RECEPTOR
SUBFAMILY V1A

Cross References:
UniProt P48043 EMBL L41502 | L41502
InterPro IPR015076 | IPR000276 | IPR001817 | IPR001224 GPCRDB V1AR_SHEEP
PRINTS PR00237 | PR00896 | PR00752 PFAM PF00001 | PF08983

Details:
NAME VASOPRESSIN AND OXYTOCIN RECEPTOR_V1A_Ovis aries
DESCRIPTION Vasopressin V1a receptor (V1aR) (Vascular/hepatic-type argininevasopressin receptor) (Antidiuretic hormone receptor 1a) (AVPR V1a).
SPECIES Ovis aries COMMON NAME Sheep NCBI Taxonomy 9940
GENE AVPR1A
SEQUENCE
MRFSGSPSPGPSNSSRWWPLDAGDANTSGDLAGLGEDGGPQADTRNEELAKLEIAVLAVI
FVVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQLGWDITYRFRGPD
GLCRVVKHMQVFAMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVL
STPQYFVFSMVEVSNVTKTYDCWANFIHPWGLPAYVTWMTGSVFVAPVVILGTCYGFICY
HIWRKVRGKTAGRQGGPAEGAGESALYRGVLHARCVSSVKTISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSAWDKNFSWVESENPATAIPALLASLNSCCNPWIYMFFSGHLLQDCA
QSFPCCQNVKRTFTREGSDSMSRRQTSFTNNRSPTNSMGTWKDSPKSSKSIKFIPVST
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12554793
HETERODIMER INFORMATION Forms functional heterodimers with V2 Receptors METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12554793
HETERODIMER INFORMATION Forms functional heterodimers with OT Receptors METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12554793

Coupling with G-proteins:
No information


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory