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gpDB::GPCR View
Entry 1 of 1 :: GPCR0258 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADRENOCEPTOR (A2-ADRENOCEPTOR)
SUBFAMILY A2B(Adrenoceptor)

Cross References:
UniProt P18089 | Q4TUH9 | Q53RF2 | Q9BZK0 EMBL M34041 | AF316895 | AF005900 | AY548167 | DQ057076 | AC092603 | M38742
InterPro IPR015695 | IPR000207 | IPR002233 | IPR000276 PDB 2CVA GPCRDB ADA2B_HUMAN
GENEID 151 MIM 104260
PRINTS PR01103 | PR00559 | PR00237 PFAM PF00001

Details:
NAME ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2B(Adrenoceptor)_Homo sapiens
DESCRIPTION Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor) (Alpha-2 adrenergic receptor subtype C2).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ADRA2B | ADRA2L1 | ADRA2RL1
SEQUENCE 
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
 FRAGMENT NO

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Scaffold:
TYPE 15-3-3 ksi REFERENCES 10224112
TYPE GASP( GPCR associated sorting protein) REFERENCES 12142540
TYPE Spinophilin/neurabin II REFERENCES 11154706

Coupling with G-proteins:
Family:Gi/o REFERENCES:2164221
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory