gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2786 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY RELAXIN RECEPTOR
SUBFAMILY LRR

Cross References:
UniProt Q9HBX9 | Q2M215 | Q3KU24 | Q3KU25 | Q3KU26 EMBL AF190500 | AY899848 | AY899849 | AY899850 | CH471056 | BC112142 | BC113617
InterPro IPR000276 | IPR002172 | IPR001611 | IPR000372 | IPR003591 | IPR008112 PDB 2JM4 GPCRDB RXFP1_HUMAN
GENEID 59350 MIM 606654
PRINTS PR00237 | PR00019 | PR01739 PFAM PF00001 | PF00057 | PF00560

Details:
NAME RELAXIN RECEPTOR_LRR_Homo sapiens-2
DESCRIPTION Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-richrepeat-containing G-protein coupled receptor 7).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE RXFP1 | LGR7
SEQUENCE
MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRA
VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY
LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK
PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL
DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQ
RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC
FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM
ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF
IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG
SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT
ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV
EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
FRAGMENT NO

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Coupling with G-proteins:
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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory