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gpDB::GPCR View
Entry 1 of 1 :: GPCR2806 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY SMOOTHENED
SUBFAMILY smoothened

Cross References:
UniProt Q90X26 EMBL AY029808
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000583 | IPR000832 GPCRDB Q90X26_DANRE
GENEID 30225
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME SMOOTHENED_smoothened_Brachydanio rerio -3
DESCRIPTION Smoothened.
SPECIES Danio rerio COMMON NAME Zebrafish NCBI Taxonomy 7955
GENE smo | smoh
SEQUENCE 
MSSKRPCSIVGSFWMLWIWTATSMVARAVILHPNETIFNDFCKKSTTCEVLKYNTCLGSP
LPYTHTSLILAEDSETQEEAFEKLAMWSGLRNAPRCWAVIQPLLCAVYMPKCENGKVELP
SQHLCQATRNPCSIVERERGWPNFLKCENKEQFPKGCQNEVQKLKFNTSGQCEAPLVKTD
IQASWYKDVEGCGIQCDNPLFTEDEHSDMHSYIAVFGTITLLCTFLHLATFLADWKNSNR
YPAVILFYVNACFFIGSIGWLAQFMDGARNEIVCKSDNTMRLGEPSSTETLSCVIIFVIV
YYSLMSGVIWFVMLTYAWHTSFKALGTTHQPLSGKTSYFHLVTWSIPFILTVAILANSQV
DADSVSGICFVGYRYYEYRAGFVLAPIGFVLVIGGYFLIRGVMTLFSIKSNHPGLLSEKA
ASKINETMLRLGIFGFLAFGFVLITFGCHFYDFFNQAEWERSFREYVLCEANVTIAHQTN
KPIPECAIKNRPSLLVGKINLFSMFGTGIAMSTWVWTKATILIWKRTWFRIIGRSDDEPK
RIKKSKMIAKAFSKRKELQKDPEKELSFSMHTVSHEGPVAGINFDLNEPSIEMSSAWAQH
VTKMVARRGAILPQDISVTPTGTPIPPPEERNKLWMVEAEISPEMMKRKKKKKKRRKEVR
PAGPAADEGNPAYHRREFGPSAVPRLPKLPGHRSLVANLWEQQRQQQEEQDMLPGAFPEF
RPSCPLPYQDRYGGLGYLRNKPSSLPLANPLTLRDSMQGDLSHFQQSSWQPKGVFRHLGQ
EASMMDVGRTAVVPRADGRRGVQIHSRTNLMDAELLDADSDF
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:10835429
1GPR0005Galpha-i2-Danio rerio-2
2GPR0298Galpha-i2-Danio rerio-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory