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gpDB::GPCR View
Entry 1 of 1 :: GPCR0288 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADRENOCEPTOR (A2-ADRENOCEPTOR)
SUBFAMILY A2B(Adrenoceptor)

Cross References:
UniProt Q90WY5 EMBL AY048970
InterPro IPR015695 | IPR000207 | IPR002233 | IPR000276 GPCRDB ADA2B_DANRE
GENEID 266751
PRINTS PR01103 | PR00559 | PR00237 PFAM PF00001

Details:
NAME ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2B(Adrenoceptor)_Brachydanio rerio
DESCRIPTION Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor) (Alpha(2B)AR).
SPECIES Danio rerio COMMON NAME Zebrafish NCBI Taxonomy 7955
GENE adra2b
SEQUENCE
MDSPCPVAVGLPGHTNGTGGTSSPTCNQSMIKLAPYSPEATAAFATAITLMMLITIVGNI
LVIIAVLTSRSLRGPQNLFLVSLAAADILVATLIIPFSLANELMGYWYFRSVWCEIYLAL
DVLFCTSSIVHLCAISLDRYMSISRAVTYGPKRTPKRIKCAILVVWLISAVISFPPLLSM
NKNKGGGESGALPQCQLNDERWYILYSTIGSFFAPCLIMILVYMRIYQIAKQRTRCPPGE
PRKEAPANATTPQHKIQNGRGDETPGTLQKKARPPTLAVSQVESVQQAANTPIANNLLQA
PSTTLTPTTPCPSPSPSNSSEVAPSKSKEGKKEKKKKKNNKNKNKKEPDNNNGESMSSDS
DTEQGGRGLEVPCTPTMTPSGIHSPATMQKYRDMIATAKGAKLVARKAKQDGTPNSARRK
AMVNREKRFTFVLAVVIGVFVICWFPFFFSYSLQAVCPESCALPEPLFKFFFWIGYCNSC
LNPVIYTIFNKDFRRAFKKILCKNTKGTFF
FRAGMENT NO

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Scaffold:
TYPE 15-3-3 ksi REFERENCES 10224112
TYPE GASP( GPCR associated sorting protein) REFERENCES 12142540
TYPE Spinophilin/neurabin II REFERENCES 11154706

Coupling with G-proteins:
Family:Gi/o REFERENCES:2164221
1GPR0005Galpha-i2-Danio rerio-2
2GPR0298Galpha-i2-Danio rerio-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory