gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0300 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADRENOCEPTOR (A2-ADRENOCEPTOR)
SUBFAMILY A2C(Adrenoceptor)

Cross References:
UniProt Q90WY6 EMBL AY048969
InterPro IPR015695 | IPR000735 | IPR002233 | IPR000276 GPCRDB ADA2C_DANRE
GENEID 266752
PRINTS PR01103 | PR00560 | PR00237 PFAM PF00001

Details:
NAME ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2C(Adrenoceptor)_Brachydanio rerio
DESCRIPTION Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2Cadrenoreceptor) (Alpha(2C)AR).
SPECIES Danio rerio COMMON NAME Zebrafish NCBI Taxonomy 7955
GENE adra2c
SEQUENCE
MHNLSYASEEDTYTDTDFTPSGNSTNSTSYSPATIIGLAGLVSFLILFTIVGNVLVVIAV
LTSRALKPPQNLFLVSLASADILVATLIIPFSLANELMGYWFFGEVWCNIYLALDVLFCT
SSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKGMIVVVWLISAVISFPPLISMDRNTVD
ERRPMCQLNDHTWYILYSSIGSFFAPCVIMILVYIRIYQVAKTRTRNMSEKRRDPDGGSG
TPRLENGLSREDSRRENGHCSSSPGERKPAEDNPDADLEDSSSSDEKAKRSQNETAPSKK
DRRSSRKNSSSSKHSSRKSRASSKSLDLFSSRRKRRNTISRKKISQAREKRFTFVLAVVM
GVFVVCWFPFFFSYSLYGICREPCAIPDPLFKFFFWIGYCNSSLNPVIYTIFNQDFRRAF
QKILCKSWKRSF
FRAGMENT NO

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Scaffold:
TYPE 16-3-3 ksi REFERENCES 10224112
TYPE Spinophilin/neurabin II REFERENCES 11154706

Coupling with G-proteins:
Family:Gi/o REFERENCES:2842764
1GPR0005Galpha-i2-Danio rerio-2
2GPR0298Galpha-i2-Danio rerio-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory