gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0031 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-1B

Cross References:
UniProt P56496 EMBL AF027184
InterPro IPR002147 | IPR002231 | IPR000276 GPCRDB 5HT1B_SPAEH
PRINTS PR00513 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-1B_Spalax leucodon ehrenbergi
DESCRIPTION 5-hydroxytryptamine receptor 1B (5-HT-1B) (Serotonin receptor 1B) (5-HT1B).
SPECIES Spalax leucodon ehrenbergi COMMON NAME Ehrenberg's mole rat NCBI Taxonomy 30637
GENE HTR1B | 5HT1B
SEQUENCE
MEEPGARCAPPPPAGSQTQTPSSNLSHNCSADSYIYQDSIALPWKVLLVALLALITLATT
LSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDF
WLSSDITCCTASIMHLCVIALDRYWAITDAVEYSAKRTPRRAAVMIALVWVFSISISLPR
FFWRQAKAEEEVLDCLVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTP
NKTGKRLSRAQLISDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKL
MAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLI
NPIIYTMPNEDFKQAFHKLIRFKCTG
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 10452531
HETERODIMER INFORMATION Forms functional heterodimers when co-expressed with 5-HT-1D Receptor. METHOD Immunoprecipitation REFERENCES 10452531

Coupling with G-proteins:
No information


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athina University of Athens
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