gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0047 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-1D

Cross References:
UniProt P79400 EMBL Y11868
InterPro IPR000505 | IPR002231 | IPR000276 GPCRDB 5HT1D_PIG
PRINTS PR00514 | PR01101 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-1D_Sus scrofa-1
DESCRIPTION 5-hydroxytryptamine receptor 1D .
SPECIES Sus scrofa COMMON NAME Pig NCBI Taxonomy 9823
GENE HTR1D
SEQUENCE
AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAI
TDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIY
STCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSL
HEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVA
SLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV
FRAGMENT YES

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 10452531
HETERODIMER INFORMATION Forms functional heterodimers when co-expressed with 5-HT-1B Receptor. METHOD Immunoprecipitation REFERENCES 10452531

Coupling with G-proteins:
No information


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory