gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0533 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CANNABINOID RECEPTOR
SUBFAMILY CB1

Cross References:
UniProt Q9BYY6 EMBL AY011601
InterPro IPR002230 | IPR000810 | IPR000276 GPCRDB Q9BYY6_HUMAN
PRINTS PR00522 | PR00362 | PR00237 PFAM PF00001

Details:
NAME CANNABINOID RECEPTOR_CB1_Homo sapiens-1
DESCRIPTION Cannabinoid receptor 1 .
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CNR1
SEQUENCE 
FRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLN
PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVY
SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK
AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY
AYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVL
IICWGPLLAIMVYDVFGKMNKLIKTVFAFC
 FRAGMENT YES

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Scaffold:
TYPE FAN( factor associated with neutral sphingomyelinase activation) REFERENCES 11306675

Coupling with G-proteins:
Family:Gi/o REFERENCES:2165569
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory